PLINEST® fast is a viscoelastic, non-pyrogenic,sterile polynucleotide gel forsingle use, for intradermal infiltration. Polynucleotides are substence of natural origin thet are extracted from fish. They are highly purified and re-absorbable. In addition to their moisturising properties, they have a trophic effect on fibroblasts. This makes them useful for improving the suppleness and tonicity of the skin.

Skin proliferation
Polynucleotide compounds cause synergy with growth factors and act directly on the purinergic receptor (Adenosine A2a), inducing a proliferative response.
Anti-inflammatory effect
PDRN (polydeoxyribonucleotides) promote the production of anti-inflammatory interleukins (IL-10), and reduce the activity of pro-inflammatory ones (TNF α, HMGB-1, IL-6).
As a result:
regeneration of the epidermis,
increase in the thickness of granulation tissue,
fibroblast formation,
filling the extracellular matrix with both collagen and non-collagen components.

Promotes tissue restoration, natural hydration, increases elasticity, and significantly improves blood circulation.
Stimulates collagen production and has a pronounced antioxidant effect.
Effectively copes with signs of age and aesthetic defects around the eyes: reduces the appearance of wrinkles, dark circles and swelling under the eyes.
Gives long-term results without side effects and long recovery.

Thanks to its biochemical and viscoelastic properties, PLINEST® fast is a moisturising and trophic substance, and is therefore used mainly to improve the turgidity, suppleness and tonicity of the skin.
This effects are also capable of facilitating remodelling of areas with a high fibrous content such as
striae and scars, in the framework of treatment protocols customised by the treating physician.

Improving skin quality;
Narrowing of pores, leveling of relief;
Removing skin pastiness;
Treatment of rosacea;
Slowing down aging.

Keep out of the reach of children. Do not use the drug if the packaging is damaged. Do not use the drug after the expiration date indicated on the package. The expiration date refers to the unopened product and implies compliance with the correct storage conditions. Do not mix PLINEST® fast with other drugs. Use the drug immediately after opening the package. Any leftovers should be discarded. Disposable product, do not re-sterilize. Do not release into the environment after use. Disposal should be in accordance with generally accepted medical practice and applicable regulations. The administration of PLINEST® fast may only be carried out by specialists authorized to do so in accordance with local legislation.
Service life or shelf life - 36 months

Mastelli srl, Via Bussana Vecchia 32, 18038 Sanremo (IM) - Italy - www.mastelli.it